Uji Aktivitas Antibakteri Ekstrak Etanol Daun Pegagan (Centella asiatica (L.) Urb ) pada BakteriStaphylococcus aureus

Authors

  • Angraini Siregar Program Studi Farmasi, Fakultas Kedokteran, Kedokteran Gigi dan Ilmu Kesehatan, Universitas Prima Indonesia
  • Maya Sari Mutia Fakultas Kedokteran, Kedokteran Gigi dan Ilmu Kesehatan, Universitas Prima Indonesia
  • Ali Napiah Fakultas Kedokteran, Kedokteran Gigi dan Ilmu Kesehatan, Universitas Prima Indonesia

DOI:

https://doi.org/10.21111/pharmasipha.v6i1.7403

Keywords:

antibacterial, Centella asiatica (L.) Urb, extract, Staphylococcus aureus

Abstract

Pegagan leaves are one of the plants used as medicine with the latin name Centella asiatica (L.) Urb. The results of phyitochemical screening that have been carried out show that pegagan leaves contain tannin, steroid and flavonoid hich have an antibacterial function by inhibiting bacterial action in cell formation and even growth. The purpose of this study was to determine the activity of extract of pegagan leaf in inhibiting Staphylococcus aureus. This type of research is in experiment with 6 treatments, namely DMSO as a negative control, an chloramphenicol as positive control and pegagan leaf extract at concentrations 25%, 50%, 75% and 100%. Extraction process of pegagan leaf by maceration method and in the antibacterial test using disc diffusion. Based on the results of the study show that pegagan leaf has antibacterial effect against Staphylococcus aureus which at concetration 25% is 7.7 mm, 50% is 10.37 mm, 75% is 12.4 mm and 100% is 12.18 mm.

Downloads

Published

2022-03-31

Issue

Vol. 6 No. 1 (2022): Maret

Section

Articles

License

Authors who publish with this Journal agree to the following terms:

  1. Author retain copyright and grant the journal right of first publication with the work simultaneously licensed under a creative commons attribution license that allow others to share the work within an acknowledgement of the work’s authorship and initial publication of this journal.
  2. Authors are able to enter into separate, additional contractual arrangement for the non-exclusive distribution of the journal’s published version of the work (e.g. acknowledgement of its initial publication in this journal).
  3. Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their websites) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published works.